Antibiotics / Selective agents
METHOTREXATE
מק"ט: M0130.0001
- 1 Gram
- CAS number 59-05-2
- Molecular weight C20H22N8O5 = 454.4
- An antineoplastic agent that acts as an anti-metabolite of folic acid. Within the cell folic acid is reduced to dihydrofolic and
- tetrahydrofolic acid. Methotrexate competitively inhibits the enzyme dihydrofolate reductase and prevents the formation of
- tetrahydrofolate, which is necessary for purine and pyrimidine synthesis and consequently the formation of DNA and RNA. Most
- active against cells in the S phase.
- Storage condition
- Store dry at room temperature
- Soluble in alkaline solutions
- Protect from light
כמות:
מקט"ים נוספים:
