Antibiotics / Selective agents
5-FLUOROURACIL (5-FU)
מק"ט:
- CAS number 51-21-8 Molecular weight C4H3FN2O2 = 130.1 Assay > 98 % Loss on drying < 0.5 %
5-Fluorouracil, a pyrimydine analogue, is an antineoplastic agent that acts as an antimetabolite to uracil. - After intra-cellular conversion to the active deoxynucleotide, it interferes with the synthesis of DNA by blocking the conver-sion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase.
- Storage condition Store at 2-8 °C Soluble in water (10 g/l) Loss on drying < 0.5%
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