24-Multiwell Insert Systems, PET Membrane

24-Multiwell Insert Systems, PET Membrane

(Corning - קורנינג)

מק"ט:

  • The Corning FluoroBlok Insert System is made with a unique light-tight PET membrane that effectively blocks the transmission of light from 400-700 nm.
  • Fluorescence from labeled cells or compounds present in the top chamber of the insert system is blocked from detection in the bottom chamber by the intervening dyed membrane.
  • Once fluorescently labeled cells or compounds pass through the membrane, they are no longer shielded from the light source and are easily detected with a bottom-reading fluorescence plate reader.
  • The wide blocking range of the Corning FluoroBlok membrane allows the flexibility to choose a variety of fluorophores for chemotaxis, cell migration, tumor cell or bacterial invasion, leukocyte extravasation, cell signaling, toxicity and permeability studies for oral bioavailability and absorption assays (e.g., Caco-2 cells).
  • Save time and labor using automated fluorescence detection Eliminate cell insert manipulation—get rapid data collection without the need for plate washing or manual cell scraping and counting.
  • Chart migration of cells and molecules in realtime without dismantling or destroying the insert Increase sample throughput—automate many commonly used membrane-based cell assays and increase the efficiency, productivity and throughput of these assays in the drug discovery process Handle 24 inserts simultaneously—all 24 wells are part of a single unit that is compatible with Falcon 24 well Plates and Feeder Tray Each insert has a generous, automation-compatible sampling port.
  • When used with Falcon 24 well plates, users can sample above and below the membrane with standard 200 µL or 1000 µL pipet tips or automated fluid handler tips.
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